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Rev. panam. infectol ; 16(1): 67-70, 2014. ilus
Article in Portuguese | LILACS, SES-SP | ID: biblio-1067141

ABSTRACT

Paciente feminina, 47 anos, hipertensa e tabagista, em uso crônico de corticoide, apresentou lesões em pele e mucosa nasal, com dor local; tratado empiricamente como sinusite. Houve piora das lesões, com ulceração. Após nove meses do início dos sintomas, foi realizada biópsia da lesão, revelando o anatomopatológico uma micose cutânea sugestiva de criptococose. A paciente foi diagnosticada com infecção pelo vírus da imunodeficiência humana (HIV) e, então, internada em hospital de referência, tendo recebido tratamento com fluconazol 800mg/dia endovenoso, a seguir, fluconazol 800mg/dia oral até completar 12 semanas de tratamento. Houve resolução da lesão ulcerada e posterior fibrose da narina esquerda


A 47-year-old woman, carrier systemic hypertension, tobacco user, and chronic user of corticosteroids, showed skin and nasal mucosa lesions, with local pain; treated empirically as sinusitis. The lesions evolved with increased ulceration. After nine months of symptoms onset, the lesion was biopsied, revealing fungal skin pathology suggestive of cryptococcosis. The patient was diagnosed with an HIV infection. The patient was then hospitalized in a specialized hospital and treated with intravenous fluconazole 800mg/day, followed by fluconazole 800mg daily orally up to 12 weeks of treatment. There was resolution of the ulcerated lesion and subsequent fibrosis of the left nostril


Subject(s)
Female , Humans , Adult , Cryptococcosis , Cryptococcosis/diagnosis , Cryptococcosis/therapy , HIV Infections , Acquired Immunodeficiency Syndrome , Fluconazole , Case Reports
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